1-Alaninechlamydocin [141446-96-0]

TargetMol Chemicals

1-Alaninechlamydocin [141446-96-0]

999

141446-96-0

Chemical

Research Use Only

1-Alaninechlamydocin

C27H36N4O6

512.607

1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).

3 years

[H][C@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCCC(=O)[C@@H]1CO1)NC2=O

-20°C

12352209