
1-Arachidoyl Lysophosphatidic Acid sodium
T83879
Overview
- SupplierTargetMol Chemicals
- Product Name1-Arachidoyl Lysophosphatidic Acid sodium
- Delivery Days Customer999
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical Name1-Arachidoyl Lysophosphatidic Acid sodium
- Molecular FormulaC23H46O7P.Na
- Molecular Weight488.57
- Scientific Description1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 microM, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 microM, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferator-activated receptor gamma (PPARgamma) in a cell-free environment. This compound has also been detected in human urine.
- Shelf life instruction3 years
- SMILESO=C(OC[C@@H](O)COP(O)([O-])=O)CCCCCCCCCCCCCCCCCCC.[Na+]
- Storage Instruction-20°C
- UNSPSC12352200