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1-Arachidoyl Lysophosphatidic Acid sodium

1-Arachidoyl Lysophosphatidic Acid sodium

T83879
TargetMol Chemicals
Molecular Weight488.57
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    1-Arachidoyl Lysophosphatidic Acid sodium
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    1-Arachidoyl Lysophosphatidic Acid sodium
  • Molecular Formula
    C23H46O7P.Na
  • Molecular Weight
    488.57
  • Scientific Description
    1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 microM, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 microM, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferator-activated receptor gamma (PPARgamma) in a cell-free environment. This compound has also been detected in human urine.
  • Shelf life instruction
    3 years
  • SMILES
    O=C(OC[C@@H](O)COP(O)([O-])=O)CCCCCCCCCCCCCCCCCCC.[Na+]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200