1-Deoxysphingosine (m18:1(4E)) [193222-34-3]

TargetMol Chemicals

1-Deoxysphingosine (m18:1(4E)) [193222-34-3]

44

Chemical

Research Use Only

1-Deoxysphingosine (m18:1(4E))

C18H37NO

283.5

1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3

3 years

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](C)N

-20°C

12352200