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ProductsBack/10,11-Dehydrocurvularin [1095588-70-7]
Chemical Structure
Chemical Structure
Chemical Structure

10,11-Dehydrocurvularin [1095588-70-7]

Research Use Only
AG-CN2-0165
AdipoGen Life Sciences
CAS Number1095588-70-7
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight290.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    10,11-Dehydrocurvularin [1095588-70-7]
  • Delivery Days Customer
    10
  • CAS Number
    1095588-70-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C16H18O5
  • Molecular Weight
    290.3
  • Scientific Description
    Antibiotic [1, 2, 6]. Antifungal [6]. Nematicidal [4]. Phytotoxic [3]. TGF-beta signaling inhibitor [9] Anticancer compound [5, 6, 8, 10]. Strong activator of the heat shock response [8]. Inhibitor of the appressorium formation of M. grisea [7] - Chemical. CAS: 1095588-70-7. Formula: C16H18O5. MW: 290.3. Isolated from Aspergillus sp. Antibiotic. Antifungal. Nematicidal. Phytotoxic. TGF-beta signaling inhibitor Anticancer compound. Strong activator of the heat shock response. Inhibitor of the appressorium formation of M. grisea
  • SMILES
    C[C@H]1CCC\C=C\C(=O)C2=C(CC(=O)O1)C=C(O)C=C2O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Curvularin. Part V. The compound C16H18O5, alphabeta-dehydrocurvularin: H.D. Munro, et al.; J. Chem. Soc. C 1967, 947 (1967)
  • Isolation of alpha,beta-dehydrocurvularin from Aspergillus aureofulgens: O. Caputo & F. Viola; Planta Med. 31, 31 (1977)
  • Brefeldin A and alpha,beta-dehydrocurvularin, two phytotoxins from Alternaria zinniae, a biocontrol agent of Xanthium occidentale: M. Vurro, et al.; Plant Sci. 138, 67 (1998)
  • Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.: M. Kusano, et al.; Biosci. Biotechnol. Biochem. 67, 1413 (2003)
  • Cytotoxic and other metabolites of Aspergillus inhabiting the rhizosphere of Sonoran desert plants: J. He, et al.; J. Nat. Prod. 67, 1985 (2004)
  • Isolation and difference in anti-Staphylococcus aureus bioactivity of curvularin derivates from fungus Eupenicillium sp.: L.W. Xie, et al.; Appl. Biochem. Biotechnol. 159, 284 (2009)
  • Alternariol monomethyl ether and alpha, beta-Dehydrocurvularin from endophytic Fungi Alternaria spp. inhibit appressorium formation of Magnaporthe grisea: Y.T. Jeon, et al.; J. Kor. Soc. Appl. Biol. Chem. 53, 39 (2010)
  • Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus: Y. Xu, et al.; Appl. Environ. Microbiol. 79, 2038 (2013)
  • Inhibition of TGF-beta signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone: K. Rudolph, et al.; Cytokine 61, 285 (2013)
  • Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India: C.G. Kumar, et al.; Springerplus 2, 122 (2013)