1,10-Decanediol

MedChem Express

1,10-Decanediol

9

112-47-0

Research Use Only

99.93

C10H22O2

174.28

1,10-Decanediol is a diol compound that can react with alpha-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism[1].

OCCCCCCCCCCO

RT

12352200