12R-LOX-IN-2

MedChem Express

12R-LOX-IN-2

5

Research Use Only

99.85

C19H13NO

271.31

12R-LOX-IN-2 (compound 7b) is an inhibitor of 12R-lipoxygenase (12R-LOX). 12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and suppresses colony formation. 12R-LOX-IN-2 also reduced the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 can be used in research into psoriasis and other skin-related inflammatory diseases[1].

OC(C1=C2C=CC=C1)=CC=C2C3=NC4=CC=CC=C4C=C3

2°C to 8°C

12352200