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14-Deoxyandrographolide

T8288
TargetMol Chemicals
CAS Number4176-97-0
Product group Chemicals
Molecular Weight334.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    14-Deoxyandrographolide
  • Delivery Days Customer
    9
  • CAS Number
    4176-97-0
  • Category Supplier
    Chemical
  • Chemical Name
    14-Deoxyandrographolide
  • Molecular Formula
    C20H30O4
  • Molecular Weight
    334.45
  • Scientific Description
    14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-alfa-mediated apoptosis through the release of TNFRSF1A release.
  • Shelf life instruction
    3 years
  • SMILES
    C[C@]12[C@@]([C@@](CO)(C)[C@H](O)CC1)(CCC(=C)[C@H]2CCC=3C(=O)OCC3)[H]
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43.