1400W . dihydrochloride [214358-33-5]

AdipoGen Life Sciences

1400W . dihydrochloride

10

214358-33-5

Research Use Only

>98%

C10H15N3 . 2HCl

177.3 . 72.9

A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM) [1, 3, 4, 6]. Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 microM) [1]. Inhibits tumor growth [2]. Increases vasoconstriction to noradrenaline [7]. Improves contractile function [8]. Improves stroke outcome and decreases glutamate release [9]. Anti-inflammatory [10]. Significant AMPK activity suppressor. Review [5]. - Chemical. CAS: 214358-33-5. Formula: C10H15N3 . 2HCl. MW: 177.3 . 72.9. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM). Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 microM). Inhibits tumor growth. Increases vasoconstriction to noradrenaline. Improves contractile function. Improves stroke outcome and decreases glutamate release. Anti-inflammatory. Review.

[Cl-].[Cl-].CC(=N)[NH2+]CC1=CC=CC(C[NH3+])=C1

2°C to 8°C

12352200