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(±)14(15)-EpETE

T37234
TargetMol Chemicals
CAS Number131339-24-7
Product group Chemicals
Molecular Weight318.457
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (±)14(15)-EpETE
  • Delivery Days Customer
    1001
  • CAS Number
    131339-24-7
  • Category Supplier
    Chemical
  • Chemical Name
    (±)14(15)-EpETE
  • Molecular Formula
    C20H30O3
  • Molecular Weight
    318.457
  • Scientific Description
    EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic acid have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the omega-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined.
  • Shelf life instruction
    3 years
  • SMILES
    CC\C=C/C[C@H]1O[C@H]1C\C=C/C\C=C/C\C=C/CCCC(O)=O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200