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ProductsBack/17-Dimethylaminoethylamino Demethoxygeldanamycin [467214-20-6]

17-Dimethylaminoethylamino Demethoxygeldanamycin [467214-20-6]

Research Use Only
D4802
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 126,00
1 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    17-Dimethylaminoethylamino Demethoxygeldanamycin [467214-20-6]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO, Ethanol
  • Scientific Description
    Geldanamycin derivative; HSP90 inhibitor.; 17-DMAG, Alvespimycin
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Silva-Fernandes A, Duarte-Silva S, Neves-Carvalho A, et al. Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease. Neurotherapeutics. 2014 Jan 30. [Epub ahead of print]. PMID: 24477711. Yi B, Yang J, Wang L. The growth inhibitory effect of 17-DMAG on ALK and MYCN double-positive neuroblastoma cell line. Tumour Biol. 2013 Nov 30. [Epub ahead of print]. PMID: 24293393. Sun X, Bristol JA, Iwahori S, et al. Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. J Virol. 2013 Sep;87(18):10126-38. PMID: 23843639. Ikebe E, Kawaguchi A, Tezuka K, et al. Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice. Blood Cancer J. 2013 Aug 16;3:e132. PMID: 23955587.