18beta-Glycyrrhetyl-3-O-sulfate [10251-38-4]

TargetMol Chemicals

18beta-Glycyrrhetyl-3-O-sulfate [10251-38-4]

999

Chemical

Research Use Only

18bèta-Glycyrrhetyl-3-O-sulfate

C30H46O7S

550.75

18beta-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), is a potent inhibitor of type 2 11beta-hydroxysteroid dehydrogenase (11beta-HSD2) with an IC50 value of 0.10 microM in rat kidney microsome assays. This compound is a substrate for organic anion transporters (OAT) 1 and OAT3, exhibits anti-inflammatory properties, and holds potential for research into pseudohyperaldosteronism [1] [2].

3 years

[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](OS(O)(=O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O

-20°C

12352200