18beta-Glycyrrhetyl-3-O-sulfate

MedChem Express

18beta-Glycyrrhetyl-3-O-sulfate

10

Research Use Only

98.01

C30H46O7S

550.75

18beta-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11beta-hydroxysteroid dehydrogenase (11beta-HSD2) inhibitor with an IC50 of 0.10 microM using rat kidney microsome. 18beta-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18beta-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18beta-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research[1][2].

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@@](C)(C4)C(O)=O)C)=CC([C@]1([H])[C@@]5([C@@](C(C)([C@H](CC5)OS(=O)(O)=O)C)([H])CC2)C)=O)C

-20°C,2°C to 8°C

12352200