Bio-Connect

(±)19(20)-EpDPA

T37238
TargetMol Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (±)19(20)-EpDPA
  • Delivery Days Customer
    1001
  • Category Supplier
    Chemical
  • Chemical Name
    (±)19(20)-EpDPA
  • Scientific Description
    EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic acid have been little studied relative to arachidonate epoxygenase metabolites. (±)19(20)-EpDPA is a DHA epoxygenase metabolite, derived via epoxidation of the omega-3 double bond of DHA. The EDHF activity of (±)19(20)-EpDPA has not yet been determined. The epoxygenase metabolites of DHA have also been detected in a mouse inflammation model.
  • Shelf life instruction
    3 years
  • SMILES
    #Reference to error in column [smiles]
  • Storage Instruction
    -20°
  • UNSPSC
    12352200