(1alpha,1S,4beta)-Lanabecestat

MedChem Express

(1alpha,1S,4beta)-Lanabecestat [1384082-96-5]

10

1384082-96-5

96.01

C26H28N4O

412.53

(1alpha,1S,4beta)-Lanabecestat ((1alpha,1S,4beta)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a K i of 0.4 nM [1] .

NC(C(C)=N1)=N[C@]21C3=C(C=CC(C4=CC(C#CC)=CN=C4)=C3)C[C@]52CC[C@@H](OC)CC5

-20°C,2°C to 8°C

12352200