2-5A

MedChem Express

2-5A

999

Research Use Only

C30H40N15O25P5

1165.59

2-5A is a 5-triphosphorylated (2,5) oligoadenylate. 2-5A is an immunotransmitter that fuels RNase L immunity. 2-5A degrades viral mRNA and inhibits protein synthesis by binding to RNase L and activating its endoribonuclease activity. 2-5A can be used in RSV and cancer research[1][2][3][4].

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](OP(O)(OC[C@@H](O[C@H]([C@@H]4OP(O)(OC[C@@H](O[C@H]([C@@H]5O)N6C=NC7=C6N=CN=C7N)[C@H]5O)=O)N8C=NC9=C8N=CN=C9N)[C@H]4O)=O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3

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