2-Amino-6-chloropurine-9-(2-O-propargyl)riboside

MedChem Express

2-Amino-6-chloropurine-9-(2-O-propargyl)riboside

10

Research Use Only

2-Amino-6-chloropurine-9-(2-O-propargyl)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] . 2-Amino-6-chloropurine-9-(2-O-propargyl)riboside is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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