20S Proteasome activator 1 [2761578-18-9]

TargetMol Chemicals

20S Proteasome activator 1 [2761578-18-9]

9

Chemical

Research Use Only

20S Proteasome activator 1

99.68%

C27H19ClF2N2OS

492.97

20S Proteasome activator 1 is a 20S proteasome activator with IC50 values of 0.3 microM for trypsin-like sites, 0.7 microM for chymotrypsin-like sites, and 1.8 microM for caspase sites. It prevents the accumulation of pathogenic alpha-synuclein (A53T) mutants through translation in the cellular system, thereby reducing the probability of disease occurrence. 20S Proteasome activator 1 can be used to study neurodegenerative diseases.

3 years

C(CC(N(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)=O)N3C=4C(SC=5C3=CC=CC5)=CC=C(Cl)C4

-20°C

51202000