2G-HaloAUTAC [2241668-58-4]

TargetMol Chemicals

2G-HaloAUTAC [2241668-58-4]

9

Research Use Only

C31H43ClFN7O6

664.17

2G-HaloAUTAC (Compound tt44), a second-generation autophagy-targeting chimera (2G-HaloAUTAC), enhances the activity of autophagy-targeting chimeras (AUTAC) by substituting the L-Cysteine (L-Cys) linker with alternative structures. This compound demonstrates degradative activity against EGFP-HaloTag protein through an autophagy mechanism.

O=C1N=C(N)NC2=C1N=C(C=3C=NN(C3)CCOCCOCCOCCOCCOCCCCCCCl)N2CC4=CC=C(F)C=C4

-20°C

12352200