3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid

MedChem Express

3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid

9

Research Use Only

C36H60N4O3

596.89

3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing[1].

CC(O[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C(NCCCNC(N)=N)=O)[C@@]4([H])CC(C)(C)CC5)([H])C1(C)C)=O

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