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3′-Azido-3′-deoxythymidine [30516-87-1]

Research Use Only
A3212
LKT Laboratories
Product group Chemicals
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    3′-Azido-3′-deoxythymidine [30516-87-1]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    Nucleoside (thymidine) analog; DNA chain terminator.; AZT, Azidothymidine, Zidovudine, ZDV, ZVD
  • UNSPSC
    12352200

References

  • Banerjee A, Abdelmegeed MA, Jang S, et al. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS One. 2013 Oct 11;8(10):e76850. PMID: 24146933. Parker WB, White EL, Shaddix SC, et al. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs. J Biol Chem. 1991 Jan 25;266(3):1754-62. PMID: 1703154. Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A. 1986 Nov;83(21):8333-7. PMID: 2430286.