3-Guanidinopropionic acid [353-09-3]

AdipoGen Life Sciences

3-Guanidinopropionic acid [353-09-3]

10

353-09-3

Research Use Only

>98%

Warning

C4H9N3O2

131.1

Chemical. CAS: 353-09-3. Formula: C4H9N3O2. MW: 131.1. Synthetic. Competitive creatine uptake inhibitor. Creatine analog that alters skeletal muscle energy expenditure. Thermogenesis inhibitor. Inhibitor of energy expenditure through reduction of ATP. AMPK stimulator and PGC-1alpha activator. Reduces cellular ATP, creatine and phosphocreatine levels, consequently stimulating AMP-activated protein kinase (AMPK) and activating PPARgamma coactivator 1alpha (PGC-1alpha). Evokes a shift from glycolytic to oxidative metabolism, increased cellular glucose uptake and increased fatigue tolerance. Ameliorates hyperglycemia in animal models of non-insulin-dependent diabetes (NIDDM). Improved insulin sensitivity and promoted weight loss selectively from adipose tissue. Studied for potential use during protein refolding as an anti-aggregatory molecule similar to L-arginine. - Competitive creatine uptake inhibitor. Creatine analog that alters skeletal muscle energy expenditure. Thermogenesis inhibitor. Inhibitor of energy expenditure through reduction of ATP. AMPK stimulator and PGC-1alpha activator. Reduces cellular ATP, creatine and phosphocreatine levels, consequently stimulating AMP-activated protein kinase (AMPK) and activating PPARgamma coactivator 1alpha (PGC-1alpha). Evokes a shift from glycolytic to oxidative metabolism, increased cellular glucose uptake and increased fatigue tolerance. Ameliorates hyperglycemia in animal models of non-insulin-dependent diabetes (NIDDM). Improved insulin sensitivity and promoted weight loss selectively from adipose tissue. Studied for potential use during protein refolding as an anti-aggregatory molecule similar to L-arginine.

NC(NCCC(O)=O)=N

-20°C,2°C to 8°C

12352200