3-Hydroxypterostilbene

Selleck Chemicals

3'-Hydroxypterostilbene [475231-21-1]

9

Research Use Only

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3-Hydroxypterostilbene (3-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 microM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.

-80°C

12352200