3-Hydroxyterphenyllin [66163-76-6]

TargetMol Chemicals

3-Hydroxyterphenyllin [66163-76-6]

16

66163-76-6

Chemical

Research Use Only

3-Hydroxyterphenyllin

C20H18O6

354.35

3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 microg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 microM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 microg/ml for both).3 It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 microM, respectively).4

3 years

COc1cc(c(OC)c(O)c1-c1ccc(O)c(O)c1)-c1ccc(O)cc1

-20°C

12352200