3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine

Toronto Research Chemicals

3-Keto-N-aminoethyl-N-aminocaproyldihydrocinnamoyl Cyclopamine [306387-90-6]

15

Chemical

Research Use Only

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ”Я-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.KAAD-Cyclopamine compound is unstable in solution.

46414

-20°C

12352200