33-cGAMP (sodium salt)

TargetMol Chemicals

33-cGAMP (sodium salt)

999

Chemical

Research Use Only

3'3'-cGAMP (sodium salt)

33-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 35-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 33-cGAMP shows weaker binding to the adapter protein stimulator of interferon genes (STING; Kd = 1.04 microM) than 22-cGAMP and 23-cGAMP but has similar binding affinity to 32-cGAMP (Kd = 1.61 microM) and cyclic di-GMP . 33-cGAMP induces IFN-beta mRNA expression in L929 cells (EC50 = 40.5 nM).

3 years

-20°C

12352200