3,4-Dichloroisocoumarin

MedChem Express

3,4-Dichloroisocoumarin [51050-59-0]

14

51050-59-0

Research Use Only

99.72

C9H4Cl2O2

215.03

3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (Ki for SrLip: 26.6 microM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms[1][2][3][4][5].

ClC1=C(OC(C2=C1C=CC=C2)=O)Cl

-20°C,2°C to 8°C

12352200