(3aR)-Selitrectinib

MedChem Express

(3aR)-Selitrectinib

14

Research Use Only

C20H21FN6O

380.42

(3aR)-Selitrectinib ((3aR)-LOXO-195) is an isform of Selitrectinib (HY-101977), which is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and TRKA and TRKC, respectively[1].

FC1=CN=C(CCC(N2)C)C([C@](CCC3)([H])N3C(C=CN4N=C5)=NC4=C5C2=O)=C1

2°C to 8°C

12352200