4-1BB/TNFRSF9, Human (Biotinylated, HEK293, His-Avi)
HY-P78067
Protein IDQ07011
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product Name4-1BB/TNFRSF9, Human (Biotinylated, HEK293, His-Avi)
- Delivery Days Customer10
- CertificationResearch Use Only
- Protein IDQ07011
- Protein NameTumor necrosis factor receptor superfamily member 9
- Scientific Description4-1BB (CD137; TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily[1]. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment[2]. 4-1BB is also involved in enhancing Nrf2 and NF-kappaB pathway mediated apoptosis of endothelial cells[3]. Human 4-1BB protein is a surface glycoprotein with a transmembrane domain (187-213 a.a.). 4-1BB/TNFRSF9 Protein, Human (Biotinylated, HEK293, His-Avi) is the extracellular part (L24-Q186) of 4-1BB protein, produced by HEK293 cells with C-terminal His- and Avi-tag.
- UNSPSC12352202