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4-1BB/TNFRSF9, Human (HEK293, Fc-Avi)

HY-P78386
MedChem Express
Protein IDQ07011
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    4-1BB/TNFRSF9, Human (HEK293, Fc-Avi)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Protein IDQ07011
  • Protein Name
    Tumor necrosis factor receptor superfamily member 9
  • Scientific Description
    4-1BB (CD137; TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily [1] . 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment [2] . 4-1BB is also involved in enhancing Nrf2 and NF-kappaB pathway mediated apoptosis of endothelial cells [3] . Human 4-1BB protein is a surface glycoprotein with a transmembrane domain (187-213 a.a.). 4-1BB/TNFRSF9 Protein, Human (HEK293, Fc-Avi) is the extracellular part (L24-Q186) of 4-1BB protein, produced by HEK293 cells with C-terminal Avi- and hFc-tag.
  • UNSPSC
    12352202