4-C18 EGCG

MedChem Express

4-C18 EGCG

9

Research Use Only

C40H54O11

710.85

4-C18 EGCG is a potent inhibitor of alpha-amylase and alpha-glucosidase with IC50 values of 3.74 and 0.81 microM, respectively. 4-C18 EGCG inhibits carbohydrate hydrolases, reduces oxidative stress and inflammation, and exhibits antidiabetic activity. 4-C18 EGCG also downregulates proinflammatory cytokines and is cytotoxic to primary human peripheral blood mononuclear cells (PBMCs), non-cancer cell lines 3T3-L1, and HEK 293 at 50 microM[1].

OC(C(O)=C1)=C(O)C=C1[C@@H](O2)[C@H](OC(C3=CC(O)=C(OCCCCCCCCCCCCCCCCCC)C(O)=C3)=O)CC4=C2C=C(O)C=C4O

12352200