4′-Demethylepipodophyllotoxin [6559-91-7]
D1849
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product Name4′-Demethylepipodophyllotoxin [6559-91-7]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Scientific DescriptionPodophyllotoxin derivative found in Podophyllum; topoisomerase II inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Xiao L, Zhao W, Li HM, et al. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways. Eur J Med Chem. 2014 Jun 10;80:267-77. PMID: 24793877. Yang TM, Guo SF, Chen CR, et al. Anti-osteosarcoma effects and mechanisms of 4-O-amino-phenol-4'-demethylepipodophyllotoxin ether. J Pharm Pharmacol. 2008 Feb;60(2):179-88. PMID: 18237465.