4-P-PDOT

MedChem Express

4-P-PDOT [134865-74-0]

5

134865-74-0

99.80

C19H21NO

279.38

4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity) [1] [2] [3] [4] .

CCC(NC1CC2=C(C=CC=C2)C(C3=CC=CC=C3)C1)=O

-20°C

12352200