5-Azidomethyl-2-deoxyuridine [59090-48-1]

MedChem Express

5-Azidomethyl-2-deoxyuridine [59090-48-1]

10

59090-48-1

Research Use Only

99.67

C10H13N5O5

283.24

5-Azidomethyl-2-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells.[1]. 5-Azidomethyl-2-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(C(CN=[N+]=[N-])=CN1[C@H]2C[C@H](O)[C@@H](CO)O2)NC1=O

-20°C

41115811