5-Deoxy-5-fluorocytidine [66335-38-4]

MedChem Express

5-Deoxy-5-fluorocytidine [66335-38-4]

10

66335-38-4

Research Use Only

99.91

C9H12FN3O4

245.21

5-Deoxy-5-fluorocytidine (5-Fluoro-5-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer[1][2][3][4].

O=C(N=C(N)C(F)=C1)N1[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O

2°C to 8°C

12352200