5-Guanidinonaltrindole (hydrochloride)

MedChem Express

5-Guanidinonaltrindole (hydrochloride) [351183-88-5]

5

351183-88-5

Research Use Only

98.72

C27H31Cl2N5O3

544.47

5-Guanidinonaltrindole (5-GNTI) hydrochloride is a highly selective and potent kappa-opioid receptor antagonist with a K i of 0.18 nM for human kappa-opioid receptor [1] .

NC(NC1=CC2=C(NC3=C2C[C@]([C@]4([H])N(CC5CC5)CC6)(O)[C@]76[C@@]3([H])OC8=C(O)C=CC(C4)=C87)C=C1)=N.[H]Cl.[H]Cl

-20°C

12352200