5-HT2A/5-HT2C inverse agonist 1

MedChem Express

5-HT2A/5-HT2C inverse agonist 1

9

Research Use Only

C24H35N5O2

425.57

5-HT2A/5-HT2C inverse agonist 1 is a potent and dual 5-HT2A and 5-HT2C receptor inverse agonist with a hERG inhibitions, thus avoiding cardiovascular risks. 5-HT2A/5-HT2C inverse agonist 1 shows significant antipsychotic efficacy in the MK-801 (HY-15084B)-induced mouse model. 5-HT2A/5-HT2C inverse agonist 1 is promising for research of psychosis[1].

CN(C=C1)N=C1CN([C@@H]2C3(CN(CC2)C)CC3)C(NCC4=CC=C(C=C4)OCCC)=O

12352200