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5-HT2B receptor antibody

Research Use Only
GTX70503
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetHTR2B

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Overview

  • Supplier
    GeneTex
  • Product Name
    5-HT2B receptor antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3357
  • Target name
    HTR2B
  • Target description
    5-hydroxytryptamine receptor 2B
  • Target synonyms
    5-HT 2B receptor; 5-HT(2B); 5-HT2B; 5-HT-2B; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B; 5-hydroxytryptamine receptor 2B variant b; serotonin receptor 2B
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
  • Reactivity
    Human, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Platelet-derived serotonin links vascular disease and tissue fibrosis. Dees C et al., 2011 May 9, J Exp Med
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