5-LO/mPGES1-IN-1

MedChem Express

5-LO/mPGES1-IN-1

5

Research Use Only

C25H25ClN4O2S2

513.07

5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 ( mPGES-1 ) and 5-lipoxygenase ( 5-LO ). IC 50 values are 0.3 and 0.4 microM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity [1] .

O=C(C(CCCCCC)SC1=NC(Cl)=CC(NC2=NC(C3=CC4=C(C=CC=C4)C=C3)=CS2)=N1)O

12352200