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5-Methylcytosine / 5-mC antibody [33D3]

GTX75897
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityOther Species
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Overview

  • Supplier
    GeneTex
  • Product Name
    5-Methylcytosine / 5-mC antibody [33D3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes 5-Methylcytosine. Clone 33D3 is specific to the methylated base and has minimal reactivity to non-methylated cytidine or cytosine (Reynaudet al.1992).
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    33D3
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Host
    Mouse
  • Isotype
    IgG1
  • Reactivity
    Other Species
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation. Wilson RL et al., 2019 Jul, Epigenetics
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  • Germline Competent Pluripotent Mouse Stem Cells Generated by Plasmid Vectors. Chen CH et al., 2016, Anim Biotechnol
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  • The exit of mouse embryonic fibroblasts from the cell-cycle changes the nature of solvent exposure of the 5-methylcytosine epitope within chromatin. elik S et al., 2014, PLoS One
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  • Nuclear DNA methylation and chromatin condensation phenotypes are distinct between normally proliferating/aging, rapidly growing/immortal, and senescent cells. Oh JH et al., 2013 Mar, Oncotarget
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  • Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells. Gertych A et al., 2010 Nov 15, Exp Cell Res
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