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Chemical Structure
Chemical Structure
Chemical Structure

5(6)-Carboxynaphthofluorescein [128724-35-6]

Research Use Only
CDX-C0047
Chemodex
CAS Number128724-35-6
Product group Chemicals
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Overview

  • Supplier
    Chemodex
  • Product Name
    5(6)-Carboxynaphthofluorescein [128724-35-6]
  • Delivery Days Customer
    10
  • CAS Number
    128724-35-6
  • Certification
    Research Use Only
  • Scientific Description
    5(6)-Carboxynaphthofluorescein (CNF) is a fluorescent NIR emitting pH indicator with red fluorescence at pH 9 (Spectral: Ex/Em: 598/668 nm). The fluorescence shifs to shorter wavelengths (Ex/Em: 512/567nm) at neutral or acidic pH environments. Spectral data: lambdaex=512nm; lambdaem=567nm (acid/neutral); lambdaex=598nm; lambdaem=668nm (basic). CNF shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. CNF has been used as an intravesicular pH probe for the colorimetric detection of activity, selectivity and cooperativity of ion channels. CNF has been used to design a luminescent probe for determination of pH, based on a Forster resonance energy transfer (FRET) system, combining a europium chelate as the donor and CNF as a pH sensitive acceptor. The FRET system enables referenced pH detection in an exceptional broad dynamic range from pH 3 to 9. - Chemical. CAS: 128724-35-6. Formula: C29H16O7. MW: 476.43. 5(6)-Carboxynaphthofluorescein (CNF) is a fluorescent NIR emitting pH indicator with red fluorescence at pH 9 (Spectral: Ex/Em: 598/668 nm). The fluorescence shifs to shorter wavelengths (Ex/Em: 512/567nm) at neutral or acidic pH environments. Spectral data: lambdaex=512nm; lambdaem=567nm (acid/neutral); lambdaex=598nm; lambdaem=668nm (basic). CNF shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. CNF has been used as an intravesicular pH probe for the colorimetric detection of activity, selectivity and cooperativity of ion channels. CNF has been used to design a luminescent probe for determination of pH, based on a Forster resonance energy transfer (FRET) system, combining a europium chelate as the donor and CNF as a pH sensitive acceptor. The FRET system enables referenced pH detection in an exceptional broad dynamic range from pH 3 to 9.
  • Storage Instruction
    RT
  • UNSPSC
    12352200