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ProductsBack/6-Amino-8-trifluoromethylphenanthridine [651055-83-3]
Chemical Structure
Chemical Structure
Chemical Structure

6-Amino-8-trifluoromethylphenanthridine [651055-83-3]

Research Use Only
AG-MR-C0031
AdipoGen Life Sciences
CAS Number651055-83-3
DownloadMSDS
Product group Chemicals
Estimated Purity>99%
Molecular Weight262.2
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    6-Amino-8-trifluoromethylphenanthridine [651055-83-3]
  • Delivery Days Customer
    10
  • CAS Number
    651055-83-3
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Hazard Information
    Warning
  • Molecular Formula
    C14H9F3N2
  • Molecular Weight
    262.2
  • Scientific Description
    Chemical. CAS: 651055-83-3. Formula: C14H9F3N2. MW: 262.2. Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation. - Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.
  • SMILES
    NC1=NC2=C(C=CC=C2)C2=C1C=C(C=C2)C(F)(F)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51202000

References

  • Isolation of drugs active against mammalian prions using a yeast-based screening assay: S. Bach, et al.; Nat. Biotechnol. 21, 1075 (2003)
  • A single step synthesis of 6-aminophenanthridines from anilines and 2-chlorobenzonitriles: F. Gug, et al.; THL 60, 4705 (2004)