6-OAU

Selleck Chemicals

6-OAU

9

Research Use Only

6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay. 6-OAU (GTPL5846, 6-n-octylaminouracil) increases [35S]GTPgammaS incorporated in Sf9 cell membranes expressing human GPR84-Galfai fusion protein with EC50 of 512 nM.

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