6PPD-Q

MedChem Express

6PPD-Q

5

Research Use Only

99.30

C18H22N2O2

298.38

6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating alpha-synuclein (alpha-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders[1].

O=C1C(NC(C)CC(C)C)=CC(C(NC2=CC=CC=C2)=C1)=O

-20°C,2°C to 8°C

12352200