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ProductsBack/7-Amino-4-trifluoromethylcoumarin [53518-15-3]
Chemical Structure
Chemical Structure
Chemical Structure

7-Amino-4-trifluoromethylcoumarin [53518-15-3]

Research Use Only
CDX-A0029
Chemodex
CAS Number53518-15-3
Product group Chemicals
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Overview

  • Supplier
    Chemodex
  • Product Name
    7-Amino-4-trifluoromethylcoumarin [53518-15-3]
  • Delivery Days Customer
    10
  • CAS Number
    53518-15-3
  • Certification
    Research Use Only
  • Scientific Description
    7-Amino-4-trifluoromethylcoumarin (AFC) is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids and therefore the precursor for a variety of AFC enzyme substrates. It is a fluorogenic standard useful as a calibration standard for AFC-based enzyme substrates and for quantitating assays monitoring 7-amino-4-trifluoromethylcoumarin (AFC) release such as those utilizing ubiquitin-AFC. Compared to AMC enzyme substrates, fluorogenic AFC substrates generate AFC that has longer absorption and fluorescence wavelength that AMC. AFC is also suitable as laser dye. Spectral Data: lambdaex 376nm, lambdaem 482nm, Quantum yield 0.531. - Chemical. CAS: 53518-15-3. Formula: C10H6F3NO2. MW: 229.16. 7-Amino-4-trifluoromethylcoumarin (AFC) is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids and therefore the precursor for a variety of AFC enzyme substrates. It is a fluorogenic standard useful as a calibration standard for AFC-based enzyme substrates and for quantitating assays monitoring 7-amino-4-trifluoromethylcoumarin (AFC) release such as those utilizing ubiquitin-AFC. Compared to AMC enzyme substrates, fluorogenic AFC substrates generate AFC that has longer absorption and fluorescence wavelength that AMC. AFC is also suitable as laser dye. Spectral Data: lambdaex 376nm, lambdaem 482nm, Quantum yield 0.531.
  • Storage Instruction
    RT
  • UNSPSC
    12352200

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