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7-Hydroxyflavone

HY-N7108
MedChem Express
CAS Number6665-86-7
Product group Chemicals
Estimated Purity99.84
Molecular Weight238.24
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Overview

  • Supplier
    MedChem Express
  • Product Name
    7-Hydroxyflavone [6665-86-7]
  • Delivery Days Customer
    5
  • CAS Number
    6665-86-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.84
  • Molecular Formula
    C15H10O3
  • Molecular Weight
    238.24
  • Scientific Description
    7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. 7-Hydroxyflavone inhibits PKM2 with an IC50 of 2.12 microM. 7-Hydroxyflavone inhibits COX-2 and 5-LOX with IC50 of 27 microg/mL and 33 microg/mL. 7-Hydroxyflavone is orally active[1][2][4].
  • SMILES
    O=C1C=C(C2=CC=CC=C2)OC3=CC(O)=CC=C13
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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