7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro-xylo-guanosine

MedChem Express

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro-xylo-guanosine

10

Research Use Only

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] . 7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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