7BIO

Selleck Chemicals

7BIO [916440-85-2]

9

Research Use Only

...

7-bromoindirubin-3-oxime (7BIO), an indirubin derivative derived from indirubin-3-oxime, possesses inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3beta (GSK3beta), also potently inhibits Abeta oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, and activation of astrocytes and microglia.

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