8-(3-Chlorostyryl)caffeine
HY-103164A
Molecular Weight330.77
Product group Chemicals
Overview
- SupplierMedChem Express
- Product Name8-(3-Chlorostyryl)caffeine
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC16H15ClN4O2
- Molecular Weight330.77
- Scientific Description8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity [1] .
- SMILESO=C(N(C1=C(C2=O)N(C(/C=C/C3=CC=CC(Cl)=C3)=N1)C)C)N2C
- UNSPSC12352200