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8-(3-Chlorostyryl)caffeine

HY-103164A
MedChem Express
Molecular Weight330.77
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    8-(3-Chlorostyryl)caffeine
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C16H15ClN4O2
  • Molecular Weight
    330.77
  • Scientific Description
    8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity [1] .
  • SMILES
    O=C(N(C1=C(C2=O)N(C(/C=C/C3=CC=CC(Cl)=C3)=N1)C)C)N2C
  • UNSPSC
    12352200