9-keto Fluprostenol isopropyl ester [1219032-18-4]

TargetMol Chemicals

9-keto Fluprostenol isopropyl ester [1219032-18-4]

16

1219032-18-4

Chemical

Research Use Only

9-keto Fluprostenol isopropyl ester

C26H33F3O6

498.5

9-Keto Fluprostenol Isopropyl Ester, an ester derivative of the FP receptor agonist fluprostenol, undergoes oxidation at carbon 9. This compound serves as a potential prodrug for 9-keto fluprostenol, which may function as an agonist at EP receptors. Additionally, it is considered a possible metabolite of fluprostenol isopropyl ester (travoprost), drawing parallels to the metabolism of latanoprost by 15-hydroxyprostaglandin dehydrogenase observed in monkey cornea. Furthermore, certain F-series prostaglandins, such as 6-keto prostaglandin F1alpha (PGF1alpha), undergo conversion to their E-series counterparts in isolated human platelets, highlighting a metabolic pathway of relevance.

3 years

C(/C=C\CCCC(OC(C)C)=O)[C@@H]1[C@@H](/C=C/[C@H](COC2=CC(C(F)(F)F)=CC=C2)O)[C@H](O)CC1=O

-20°C

12352200