9,10-trans-Dehydroepothilone D

MedChem Express

9,10-trans-Dehydroepothilone D

9

Research Use Only

C27H39NO5S

489.67

9,10-trans-Dehydroepothilone D shows an antiproliferative activity against a paclitaxel-resistant cell lines overexpressing P-glycoprotein . 9,10-trans-Dehydroepothilone D also shows tubulin polymerization activity. 9,10-trans-Dehydroepothilone D is given by lactonization of Seco acid, which is promising for research of cancers [1] .

O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C/C=C(C)\C/C=C/[C@H](C)[C@H](O)[C@@H](C)C1=O

12352200